Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2021 GMC Sierra 2500 trucks
for sale
near
Mesa, AZ
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.






Used
2021 GMC Sierra 2500 AT4
Vehicle information
Features
Reviews
Our experience was very positive.
Our experience was very positive. We went to the Dealership on 3-3-2025, spoke with salesman Brian McFadden. He was very pleasant and professional. We selected a vehicle to test drive, we liked it and made arrangements to purchase it. We liked the no nonsense, hassle free car buying. They gave us exact figures on the total price of the vehicle, we went to the back and obtained a cashiers check for the amount of the car out the door and drove away in our newer car. We are very happy with the entire experience and dealing the Brian McFadden and Brian Whitiker, mgr.
Beautiful truck
I love my 2021 GMC Denali 2500HD. I have gotten more complements on this truck than any other vehicle that I have owned. I get great highway fuel milage average 19-26mpg,which is great for a heavy duty truck!






Used
2021 GMC Sierra 2500 AT4
Vehicle information
Features
Reviews
Marcy was very helpful going through all the features.
Marcy was very helpful going through all the features. Very happy! Would definitely recommend buying with Bill luke
Best truck I ever owned
Love my GMC. Owned a Chevy and this absolutely beats it hands down. Never had any issues. Inside is very comfortable and can't imagine driving anything else






Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
I have trusted and used Henry Brown for repairs since
I have trusted and used Henry Brown for repairs since purchasing the Tahoe from their CASA Grande, AZ store in 2009. First with Mike Meade and now with Lou. Both very professional, knowledgeable and helpful.
GMC 2500 HD AT4
This is the first diesel I have owned. The power is amazing and I really like the room inside the cab. This truck is a beast... Love it!






Vehicle information
Features
Reviews
Fantastic dealership, highly recommend, They do a great
Fantastic dealership, highly recommend, They do a great job! getting you what you want at the best price,
Never had one. Always wanted one and love it.
I love my Denali. Beautiful truck inside out. When I drive down the road all heads turn. I couldn't have made a better choice. That's Cortez for you good service.






GMC Certified
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
I recently purchased a 2025 Chevy Traverse, and I
I recently purchased a 2025 Chevy Traverse, and I couldn't be happier with the outstanding service I received from the team at Courtesy Chevrolet. From start to finish, the experience was exceptional!!! Jackson, my sales person, was incredibly knowledgeable and attentive. He took the time to understand my needs and preferences, ensuring that the Traverse was the perfect fit for me. His expertise and friendly demeanor made the buying process smooth and enjoyable. Miguel in finance was a true professional, guiding me through the financing options with ease. He made sure I understood every detail and helped customize a plan that worked best for me. Miguel's commitment to customer satisfaction was evident in every interaction. Jessie in parts and accessories went above and beyond to help me personalize my new vehicle. His suggestions were spot-on, and she ensured that everything was ordered and installed promptly. Overall, the team at Courtesy Chevrolet exceeded my expectations with their excellent service and attention to detail. I highly recommend them to anyone in the market for a new vehicle. Thank you to Jackson, Miguel, and Jessie for making my purchase a memorable and pleasant experience!
Early to tell truck has less than 100 miles
Truck was bought specifically to our travel trailer. We have to wait for 1000 break in before we can tow the trailer. So far the truck is very quiet, smooth running, & comfortable to drive. We were pleasantly surprised at how much interior storage space is available. Having the bed steps before rear tires and in the bumper sides is very nice. Bed rails are even with my shoulders so the steps get used a lot.






GMC Certified
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Great deal from Coulter
Coulter dealerships have been very good to me with the vehicles I have bought from them in the past. Coulter Cadillac was the best experience yet. I got a great deal and I know it! The deal was mostly done on line and did not change the day the xt6 was picked up. This is not the usual dealership experience. No wonder Coulter has been around for 100 years. Thank you very much, Steve and Nancy






Used
2021 GMC Sierra 2500 Denali Ultimate
Vehicle information
Features
Reviews
contacted me gave me the info on the freestar i decided
contacted me gave me the info on the freestar i decided it was not the right van for me






Used
2021 GMC Sierra 2500 Base
Vehicle information
Features
-
Prev - 1
-
Next
GMC Sierra 2500 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 GMC Sierra 2500 | $45,895 | 1 Good deal |
2024 GMC Sierra 2500 | $39,900 | 2 Good deals |
About the 2021 GMC Sierra 2500
Base shown (base trim).
- Seating
- 3
- Door count
- 2
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 0
- Transmission
- 6-Speed A/T
- Engine
- 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel)

How much does the 2021 GMC Sierra 2500 cost?
The 2021 GMC Sierra 2500 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 Sierra 2500 is $55,894, with pricing starting at $28,633.
What are some similar vehicles and competitors of the 2021 GMC Sierra 2500?
The 2021 GMC Sierra 2500 compares to and/or competes against the following vehicles:
Is the 2021 GMC Sierra 2500 reliable?
The 2021 GMC Sierra 2500 has an average reliability rating of 4.1 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 Sierra 2500 owners.
Is the 2021 GMC Sierra 2500 a good truck?
Below are the Cars.com consumer ratings for the 2021 GMC Sierra 2500.
- Comfort 4.8
- Interior 4.6
- Performance 4.4
- Value 4.0
- Exterior 4.6
- Reliability 4.1
78% of drivers recommend this car
- Comfort 4.8
- Interior 4.6
- Performance 4.4
- Value 4.0
- Exterior 4.6
- Reliability 4.1
AT4 (2 styles)
Style | |
---|---|
4WD Crew Cab 172" AT4 | 4WD Crew Cab 159" AT4 |
Inventory price | |
Starting at $59,300 | Starting at $59,100 |
Combined MPG | |
0 | 0 |
Engine | |
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Base (10 styles)
Style | |||||||||
---|---|---|---|---|---|---|---|---|---|
4WD Crew Cab 159" | 2WD Crew Cab 172" | 4WD Crew Cab 172" | 2WD Crew Cab 159" | 2WD Double Cab 162" | 4WD Double Cab 162" | 4WD Double Cab 149" | 2WD Double Cab 149" | 2WD Reg Cab 142" | 4WD Reg Cab 142" |
Inventory price | |||||||||
Starting at $43,400 | Starting at $40,800 | Starting at $43,600 | Starting at $40,600 | Starting at $39,000 | Starting at $41,800 | Starting at $41,600 | Starting at $38,800 | Starting at $36,200 | Starting at $39,000 |
Combined MPG | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Denali (2 styles)
Style | |
---|---|
4WD Crew Cab 172" Denali | 4WD Crew Cab 159" Denali |
Inventory price | |
Starting at $65,700 | Starting at $65,500 |
Combined MPG | |
0 | 0 |
Engine | |
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLE (10 styles)
Style | |||||||||
---|---|---|---|---|---|---|---|---|---|
2WD Crew Cab 172" SLE | 4WD Crew Cab 159" SLE | 2WD Crew Cab 159" SLE | 4WD Crew Cab 172" SLE | 2WD Double Cab 162" SLE | 2WD Double Cab 149" SLE | 4WD Double Cab 149" SLE | 4WD Double Cab 162" SLE | 4WD Reg Cab 142" SLE | 2WD Reg Cab 142" SLE |
Inventory price | |||||||||
Starting at $45,600 | Starting at $48,200 | Starting at $45,400 | Starting at $48,400 | Starting at $43,800 | Starting at $43,600 | Starting at $46,400 | Starting at $46,600 | Starting at $44,400 | Starting at $41,600 |
Combined MPG | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLT (8 styles)
Style | |||||||
---|---|---|---|---|---|---|---|
4WD Double Cab 162" SLT | 2WD Double Cab 149" SLT | 2WD Double Cab 162" SLT | 4WD Double Cab 149" SLT | 4WD Crew Cab 159" SLT | 2WD Crew Cab 159" SLT | 2WD Crew Cab 172" SLT | 4WD Crew Cab 172" SLT |
Inventory price | |||||||
Starting at $54,600 | Starting at $51,600 | Starting at $51,800 | Starting at $54,400 | Starting at $56,200 | Starting at $53,400 | Starting at $53,600 | Starting at $56,400 |
Combined MPG | |||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
Research the 2021 GMC Sierra 2500
Compare the 2021 GMC Sierra 2500
- ${price_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
Certified cars are manufacturer warrantied and typically go through a rigorous multi-point inspection.
This car is likely to sell soon based on the price, features, and condition.
${award_blurb}
${award_two_blurb}